May 2025 Newsletter

April 29, 2025

By Shao Li

Upcoming conference

I am excited to share that I will be participating as a teaching assistant for the Analytical and Quantitative Light Microscopy (AQLM) course at the Marine Biological Laboratory (MBL) in Woods Hole, Massachusetts. AQLM is a comprehensive and intensive course in light microscopy for researchers in biology, medicine, and material sciences. This course provides a systematic and in-depth examination of the theory of image formation and application of digital methods for exploring subtle interactions between light and the specimen. Running from April 30 to May 9, 2025, the course is directed by Dr. Peter Kner (University of Georgia) and Dr. Alexa Mattheyses (University of Alabama, Birmingham), with laboratory direction by Dr. Emily Bartle (University of North Carolina). The course will cover a wide range of topics including phase contrast microscopy, polarization microscopy, interference microscopy, confocal microscopy, FRET, FLIM, TIRF, SIM, STORM, and others. Students will attend lectures and take part in extensive hands-on laboratory sessions. They will work directly with modern optical and digital imaging equipment and learn quantitative methods essential for proper image interpretation.

Image analysis update

We have been collaborating with Matthew Kwan from Shields Lab to quantify the PLGA/Silica particles in biological samples. With Imaris, we optimized segmentation parameters to more accurately distinguish the PLGA signal with adaptive thresholding.

Image of cells
Source: Matt Kwan/Shields Lab

If you are working with fluorescent materials or polymer systems and would like support for image analysis, please reach out to our team. We are happy to assist with customizing workflows for your specific samples.

Recent publications